Use disease-free seeds. Treatments of infected seeds based on copper + mancozeb, 1% peroxyacetic acid, and 1% sodium hypochlorite, would make it possible to disinfect them more or less effectively.
Do not collect seeds from diseased fruits and use them later. Certainly partially contaminated, they will ensure early contamination of plants, probably already in the nursery.
Use healthy plants. The bacterium seems capable of causing lesions on the cotyledons of certain Cucurbitaceae.
Do not work in the crop when the plants are wet.
Avoid sprinkling irrigations, or carry them out in the morning or during the day, but never in the evening. Thus, the aerial organs (leaves and fruits) will dry out quickly.
Destroy plant debris and especially rotten fruit by burning them, or by burying them deeply.
Carry out rotations of at least 3 years with non-host plants, which should not pose a problem because this bacteriosis is very specific to Cucurbitaceae.